Environment, Geochemistry and the Etiology of Balkan Endemic Nephropathy: Lessons from Romania
نویسندگان
چکیده
US Geological Survey, 12201 Sunrise Valley Drive, MS 956, Reston, VA 20192, U.S.A. Department of Immunology, Clinical Laboratory No.1, Pta. E. Murgu No.2, RO-1900 Timisoara, Romania Florida Community College at Jacksonville, Jacksonville, FL 32256,U.S.A. Department of Environmental & Toxicologic Pathology, Armed Forces Institute of Pathology, 14th and Alaska Ave. N.W., Washington, D.C. 20306-6000, U.S.A Center of Hemodialysis, County Hospital, 82 Unirii Str., RO-1500, Drobeta Turnu Severin, Romania * E-mail: [email protected]
منابع مشابه
Organic compounds in water extracts of coal: links to Balkan endemic nephropathy
The Pliocene lignite hypothesis is an environmental hypothesis that has been proposed to explain the etiology of Balkan endemic nephropathy (BEN). Aqueous leaching experiments were conducted on a variety of coal samples in order to simulate groundwater leaching of organic compounds, and to further test the role of the Pliocene lignite hypothesis in the etiology of BEN. Experiments were performe...
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Background Balkan endemic nephropathy (BEN) is an irreversible, chronic, tubulo-interstitial nephropathy of unknown origin, geographically confined to several rural regions of the Balkan Peninsula. The first "official" observation of a disease resembling BEN was made almost six decades ago in regions comprising the former Yugoslavia (Danilovic et al., 1957). Shortly thereafter, similar descript...
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Balkan Endemic Nephropathy occurs with a high rate of prevalence in Serbia, Bulgaria, Romania, Bosnia and Herzegovina, and Croatia. The first cases described in Bulgaria, Serbia and Romania date to the late 1950s and early 1960s. BEN has been characterized to date as a chronic, slowly progressive familial tubular interstitial renal disease of unknown aetiology. The disease is characterized by i...
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The correlation between the geographic occurrence of Balkan endemic nephropathy (BEN) and low rank Pliocene lignites is striking. Comparison of mass spectra of methanol extracts from lignite samples collected in the vicinity of two endemic villages, with mass spectra of methanol extracts higher grade coals, shows the presence of many more potentially nephrotoxic compounds, and much higher total...
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In the first issue of BANTAO J, in 2003, I have presented the current research in Balkan endemic nephropathy (BEN) and associated upper urothelial tumors (UUT). As I stated in that paper, etiology remains the main problem for research in BEN [1]. Research of BEN in the nineties was hampered by the turmoil in the Balkans, especially in the former Yugoslavia. The Program Committee of the Interaca...
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تاریخ انتشار 2002